Structural design of high-rise buildings is a professional course. Taking the construction of “Emerging Engineering Education” as an opportunity and the characteristics of curriculum knowledge system as a starting point， this paper puts forward the principles of OBE（Outcomes-based Education） orientation， CDIO standard， ideological and political education and the standard of high-level， creativity and challengingness for the reconstruction of its teaching mode， thus forming OBE + CDIO whole process teaching method， ideological and political immersion integration method and multi-dimensional project-based teaching method. It realizes the optimization and reconstruction of curriculum teaching mode， which has reference value for the steady progress of teaching reform.