The course information system analysis and design aims to cultivate students'' abilities in analyzing， designing， and developing information systems， serving as a crucial component in the development of their comprehensive competencies. Currently， the course faces issues such as low student engagement and a tendency for theory to disconnect from practice. Therefore， this paper proposes a case-based teaching approach grounded in the OBE （Outcome-Based Education） philosophy. This approach is student-oriented towards comprehensive practical abilities， integrates real-world cases across various teaching modules， and employs a "case-theory-practice" fusion model to guide students in theoretical construction. Task-driven instruction is utilized to expand the course''s teaching dimensions from the "knowledge" level to include "skills， learning attitudes， and values." Through teaching evaluations， the proposed method has achieved positive outcomes in cultivating students'' comprehensive practical abilities.