In 2005, Xichang University was promoted as the upgraded university. In order to comprehensively and objectively analyze the papers published in Journal of Xichang University (Natural Science Edition) and also learn the core authors in the journal more comprehensively, this paper selects the high cited papers which were ranked as the first 5% between the years from 2005 to 2016 in CNKI "Chinese Citation Database" and "China Academic Journal Network Publishing House" and carries on the statistical analysis according to the subject cloth, the author's identity, the fund support situation and so on. Through the analysis, especially the characteristics of the high cited papers, it proposes related measures for topic design, collection arrangement and seeking high cited author groups for the purpose to improve influence and quality of the Journal