Professional skills competition is an important mean of application-oriented talent training. Exploration and practice of professional skills competition of animal science specialty were summarized with the status of talent training in application-oriented universities with the case of Xichang College in this artical. Professional skills competition is also an important approach of stimulating the enthusiasm for learning and cultivating the comprehensive ability of the students in application-oriented talent training. In order to ensure the development of professional skills competition, the construction of evaluation system and double qualified teachers team must be enhancing in practice. Certain effectiveness of professional skills competition in the animal science specialty of Xichang College were achieved in the process of practicing.