Purpose Solution concentration is an important metrological parameter， and its determination is widely used in industries and scientific researches. To quickly and accurately determine solution concentration， we propose an energy dispersive X-ray fluorescence analysis method in this paper.Method Ten prepared ferric chloride solutions were used as standard solutions， the characteristic X-ray peak areas of Fe in the solution were determined using energy dispersive X-ray fluorescence analysis， and the standard curve of the ferric chloride solution was obtained. Five sets of ferric chloride solutions were determined using this standard curve.Result The experimental results indicate that the concentrations of ferric chloride have a good linear relationship with the characteristic X-ray peak areas of Fe determined by energy dispersive X-ray fluorescence analysis method. And the concentrations of ferric chloride of five unknown solutions are experimentally determined， the data show that the maximum error of the concentration of ferric chloride solutions is 1.74%， and the other errors are within 1%， which is less than the traditional refractive index measurement （about 3%）. In addition， to further analyse the accuracy of this method， concentration gradient differences are calculated separately. According to the gradient difference， the maximum gradient difference is 3.71%， with the majority being within 1% and the minimum being 0.Conclusion This method has high accuracy， and the data output is fast and can be obtained as needed. Therefore， this method can provide a reference for rapid and accurate determination of solution concentration.