Using the methods of literature, investigation method, mathematical statistics to investigate 273 students who took part in the sports associations of the undergraduate medical students, to understand the effect of sports club activities on mental health of medical students. The conclusion shows that medical students are not high-risk mental health disorders population; strengthening the construction of university sports associations and other sports activities of the organization is the effective way of mental health education; sports club activities choose the content and methods in line with characteristics of college students' psychological development, collective physical excercise program is more conducive to the development of students' psychological health