20 Boys and 20 girls are chosen to practice pearl ball for 12 weeks. 7 indexes including 800re（girl）, 1000m（boy）, sit and reach, the power of gripping, time reaction, weight and body fat are designed to test their vital capacity before and after eaefi game. The result shows that except their weight, all other indexes are changging positively after Pearl ball game. This indicates that pearl ball game can improve the college students＇ respiratory and cardiovascuhr system functions, muscular flexibility and strength and reduce their body fat. Therefore, pearl ball game should be introduced as part of our daily teaching contents. By doing so, it will be better disseminated and popularized, and students＇ physical and mental health will be improved as well.