DSP application technology is a comprehensive course， occupies an important position in the education programme for electronics and information engineering talents. To promote students'' learning initiative and comprehensive application ability， the teaching reform of DSP application technology experimental course based on conceive-design-implement-operate (CDIO） and project-based learning （PBL） theories is proposed， and specifically， the teaching methods， teaching materials and teaching evaluations are reformed and explored. To meet the needs of students with different abilities， two experimental projects with different levels of difficulty are designed， and students can choose a project based on their abilities. In the whole process， students play the dominant role， and teachers assist and give guidance. In this teaching model， problem scenarios are designed for students， who are guided to solve problems； meanwhile， an environment for independent inquiry is created to effectively improves students'' ability to analyze and solve problems. This model is very effective for students'' in-depth mastery of digital signal processor （DSP）-related knowledge.