Aiming at the technical problems of slow switching and large delay of optical switching array in data center， a design method of drive and control circuit for large-scale optical switching array is proposed. On the basis of introducing the principle of large-scale optical switch array drive and control circuit， a single high speed， amplitude adjustable optical switch control circuit is designed first， and then 2 000 optical switch array drive and control circuits are designed， and then the selection basis of main chips is given. Finally， the correctness of this design is verified through experiments. By creatively using two digital potentiometers and one high-speed switch， the drive control circuit design with adjustable high level and low power average is realized， which provides a reference for the design of the drive and control circuit of the optical switch array.