The practical teaching method based on engineering application cases plays an important role in the engineering teaching system. Based on the analysis of the actual situation of the plateau and the reform needs of the of the transportation curricular teaching, this paper proposes an engineering teaching model centering around engineering cases and the interaction between theory and practice. This mode is applicable to both online and offline teaching methods, which can not only help students build a theoretical knowledge system oriented to practical needs and master engineering experience, but also meet the requirements of engineering education accreditation on the abilities of transportation students and the future development needs of Tibet Autonomous Region.