The educational reform model of three-integration ICT application-oriented talent cultivation was proposed， the background of this model and the problems in ICT talent cultivation in universities in Liangshan ethnic areas were described. Taking Xichang University as an example， the practical path of this model was introduced， which includes integration of education programs， integration of industries and schools， and integration of “two educations”. Practices were done in the eight aspects： education programs， curriculum systems， teaching methods， evaluation methods， practical teachings， “double-qualified” teaching corps， professional spirit， and sense of shared community for all Chinese nationalities， so as to develop a new approach of “three-integration” ICT application-oriented talent cultivation for universities to serve local Liangshan ethnic regional development. The positive practical achievements of this model in talent cultivation， industrial development， poverty alleviation， and rural revitalization in Liangshan ethnic areas were also analyzed.