Culture is the soul of a country and nation. Inheritance and promotion of excellent traditional culture, and exploration and enrichment of architecture's cultural connotations are important parts reflecting the regional characteristics of a city. Chu-Han culture is one of the important sources of traditional Chinese culture, and it has been uninterruptedly inherited and transformed in the course of our history. In this paper, with northern Anhui as a historical region of Chu-Han culture, we examine its Chu-Han culture characteristics and try to refine the most distinctive part of Chu-Han culture through abstraction and innovation, and to merge Chu-Han art with modern architectural design to inspire current architectural design needs for regional Chu-Han style beauty.