Curriculum reform is needed for effective class instruction and college program development. Through reform of the course of Comprehensive Financial Business Practice for students in financial management program, it is found that the "training classroom + off-campus enterprise" instruction model is more effective than the "on-campus training classroom" model alone, and the "enterprise first, campus second" model is more conducive to students' learning than "campus first, enterprise second" model is. To better implement course instructions, we still need to further develop more effective teaching models.