Taking flue-cured tobacco of Yunyan 87 as test material and wheat, ryegrass, peas, Chinese trumpet creeper, rape, garlic or slack winter season as different previous crops, the effects of different previous crops on the yield and quality of flue-cured tobacco in Panzhihua area are studied. The test results show that: previous cropping of ryegrass, peas or rape is good for producing medium plant type of flue-cured tobacco; previous crop of ryegrass, Chinese trumpet creeper or rape can contribute to tobacco's higher economic returns; however, previous crop of slack winter season, ryegrass or wheat can better bring out the delicate scent of Panxi tobacco leaves. It is recommended that ryegrass is grown as the previous crop for flue-cured tobacco.