The Experimental Statistics Method Courseis very important to improve students' research ability, but it is hard for students to study taking the contents abstract to understand and the formulas difficult to memorize into consideration. In this study, Flipped Classroom teaching was carried out for students majored in Agriculture in Grade 2016 and 2017 of Anhui Science and Technology University. The results of mid-term and final examinations show that the experimental class are significantly better than other classes.The questionnaires in Experimental class show that the students have a high recognition of Flipped Classroom and believe that Flipped Classroom can significantly increase the interaction between teachers and students. In conclusion, Flipped Classroom can significantly increase the achievement of students.However, teachers should carry out flipped classroom teaching according to the actual situation