It determines the applicability of talent cultivation by popularity advance of high education and reality demand of civil engineering major talent.This paper analyzed problems of practice teaching and constructed multiple civil engineering major practice teaching system of“five dimensions in one centre”,which is in accordance with aspects of high schools, companies and students.The system is consists of one centre,two guarantees,three regulations,four measures and five modes,which takes application-orientted talent cultivation as centre, thought teaching and definition of rights and obligations as guarantees , management & assessment&monitoring as regulations, practice base expansion& practice platform establishment & separately setting courses & teaching team construction as measures, five practic modes as combination.The system is systematic and comprehensive which can also provide helpful guidance and reference for other engineering major